n a recent paper published in Cancer Discovery, Keio University’s Sara Horie and her colleagues conducted an in-depth analysis of cancer driver alterations using genomic data from Japanese and international cohorts. The study elucidates the genomic landscape of Japanese patients and identifies significant genomic differences between Asian and white populations, providing valuable resources for cancer genomic medicine. These findings have important implications for appropriate patient selection in molecularly targeted therapies. Background The advent of next-generation sequencing (NGS) has transformed...